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Preemptive perineural bupivacaine attenuates the maintenance of mechanical and cold allodynia in a rat spinal nerve ligation model
BACKGROUND: Neuropathic pain is evasive to treat once developed, however evidence suggests that local administration of anesthetics near the time of injury reduces the development of neuropathic pain. As abnormal electrical signaling in the damaged nerve contributes to the initiation and maintenance...
Autores principales: | Clifford, John L., Mares, Alberto, Hansen, Jacob, Averitt, Dayna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596364/ https://www.ncbi.nlm.nih.gov/pubmed/26444970 http://dx.doi.org/10.1186/s12871-015-0113-x |
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