Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) have a remarkable capacity to maintain normal genome stability and karyotype in culture. We previously showed that infrequent bursts of Zscan4 expression (Z4 events) are important for the maintenance of telomere length and genome stability in mESCs. However, the mo...

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Detalles Bibliográficos
Autores principales: Akiyama, Tomohiko, Xin, Li, Oda, Mayumi, Sharov, Alexei A., Amano, Misa, Piao, Yulan, Cadet, J. Scotty, Dudekula, Dawood B., Qian, Yong, Wang, Weidong, Ko, Shigeru B. H., Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596397/
https://www.ncbi.nlm.nih.gov/pubmed/26324425
http://dx.doi.org/10.1093/dnares/dsv013

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