Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia

BACKGROUND: Specific genes, such as BCAT1 and IKZF1, are methylated with high frequency in colorectal cancer (CRC) tissue compared to normal colon tissue specimens. Such DNA may leak into blood and be present as cell-free circulating DNA. We have evaluated the accuracy of a novel blood test for thes...

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Detalles Bibliográficos
Autores principales: Pedersen, Susanne K., Symonds, Erin L., Baker, Rohan T., Murray, David H., McEvoy, Aidan, Van Doorn, Sascha C., Mundt, Marco W., Cole, Stephen R., Gopalsamy, Geetha, Mangira, Dileep, LaPointe, Lawrence C., Dekker, Evelien, Young, Graeme P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596413/
https://www.ncbi.nlm.nih.gov/pubmed/26445409
http://dx.doi.org/10.1186/s12885-015-1674-2

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