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Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia
Hypoxia-ischaemia (HI) is a major cause of neonatal brain injury, often leading to long-term damage or death. In order to improve understanding and test new treatments, piglets are used as preclinical models for human neonates. We have extended an earlier computational model of piglet cerebral physi...
Autores principales: | Caldwell, Matthew, Moroz, Tracy, Hapuarachchi, Tharindi, Bainbridge, Alan, Robertson, Nicola J., Cooper, Chris E., Tachtsidis, Ilias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596480/ https://www.ncbi.nlm.nih.gov/pubmed/26445281 http://dx.doi.org/10.1371/journal.pone.0140171 |
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