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Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil: data from the Brazilian Type 1 Diabetes Study Group

BACKGROUND: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical chara...

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Detalles Bibliográficos
Autores principales: Felício, João Soares, de Souza, Ana Carolina Contente Braga, Koury, Camila Cavalcante, Neto, João Felício Abrahão, Miléo, Karem Barbosa, Santos, Flávia Marques, Motta, Ana Regina Bastos, Silva, Denisson Dias, Arbage, Thaís Pontes, Carvalho, Carolina Tavares, de Rider Brito, Hana Andrade, Yamada, Elizabeth Sumi, Cobas, Roberta Arnoldi, Matheus, Alessandra, Tannus, Lucianne, Palma, Catia Cristina Sousa, Japiassu, Leticia, Carneiro, João Regis Ivar, Rodacki, Melanie, Zajdenverg, Lenita, de Araújo, Neuza Braga Campos, de Menezes Cordeiro, Marilena, Luescher, Jorge Luiz, Berardo, Renata Szundy, Nery, Marcia, Cani, Catarina, do Carmo Arruda Marques, Maria, Calliari, Luiz Eduardo, de Noronha, Renata Maria, Manna, Thais Della, Savoldelli, Roberta, Penha, Fernanda Garcia, Foss, Milton Cesar, Foss-Freitas, Maria Cristina, Pires, Antonio Carlos, Robles, Fernando Cesar, Negrato, Carlos Antonio, de Fatima Guedes, Maria, Dib, Sergio Atala, Dualib, Patricia, da Silva, Saulo Cavalcanti, Sepúlveda, Janice, Sampaio, Emerson, Rea, Rosangela Roginski, de Almeida Faria, Ana Cristina Ravazzani, Tschiedel, Balduino, Lavigne, Suzana, Cardozo, Gustavo Adolfo, Azevedo, Mirela, Canani, Luis Henrique, Zucatti, Alessandra Teixeira, Coral, Marisa Helena Cesar, Pereira, Daniela Aline, de Araujo, Luiz Antonio, Pedrosa, Hermelinda Cordeiro, Tolentino, Monica, Prado, Flaviene Alves, Rassi, Nelson, de Araujo, Leticia Bretones, Fonseca, Reine Marie Chaves, Guedes, Alexis Dourado, de Mattos, Odelisa Silva, Faria, Manuel, Azulay, Rossana, e Forti, Adriana Costa, Façanha, Cristina Figueiredo Sampaio, Junior, Renan Montenegro, Montenegro, Ana Paula, Melo, Naira Horta, Rezende, Karla Freire, Ramos, Alberto, Jezini, Deborah Laredo, Gomes, Marilia Brito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596564/
https://www.ncbi.nlm.nih.gov/pubmed/26448787
http://dx.doi.org/10.1186/s13098-015-0081-9
Descripción
Sumario:BACKGROUND: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. METHODS: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. RESULTS: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North-Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. CONCLUSIONS: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities.