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CD98 Heavy Chain Is a Potent Positive Regulator of CD4(+) T Cell Proliferation and Interferon-γ Production In Vivo
Upon their recognition of antigens presented by the MHC, T cell proliferation is vital for clonal expansion and the acquisition of effector functions, which are essential for mounting adaptive immune responses. The CD98 heavy chain (CD98hc, Slc3a2) plays a crucial role in the proliferation of both C...
Autores principales: | Kurihara, Takeshi, Arimochi, Hideki, Bhuyan, Zaied Ahmed, Ishifune, Chieko, Tsumura, Hideki, Ito, Morihiro, Ito, Yasuhiko, Kitamura, Akiko, Maekawa, Yoichi, Yasutomo, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596652/ https://www.ncbi.nlm.nih.gov/pubmed/26444422 http://dx.doi.org/10.1371/journal.pone.0139692 |
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