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Structural determinants of nuclear export signal orientation in binding to exportin CRM1

The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals (NESs), which are highly variable in sequence and structure. The plasticity of the CRM1-NES interaction is not well understood, as there are many...

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Detalles Bibliográficos
Autores principales:	Fung, Ho Yee Joyce, Fu, Szu-Chin, Brautigam, Chad A, Chook, Yuh Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596688/ https://www.ncbi.nlm.nih.gov/pubmed/26349033 http://dx.doi.org/10.7554/eLife.10034

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