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Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency

The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously identified the Mediator subunit, MED28, as a cytosolic binding partner of merlin, t...

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Detalles Bibliográficos
Autores principales: Li, Lin, Walsh, Ryan M., Wagh, Vilas, James, Marianne F., Beauchamp, Roberta L., Chang, Yuh-Shin, Gusella, James F., Hochedlinger, Konrad, Ramesh, Vijaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596692/
https://www.ncbi.nlm.nih.gov/pubmed/26445504
http://dx.doi.org/10.1371/journal.pone.0140192