Cargando…
Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency
The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously identified the Mediator subunit, MED28, as a cytosolic binding partner of merlin, t...
Autores principales: | Li, Lin, Walsh, Ryan M., Wagh, Vilas, James, Marianne F., Beauchamp, Roberta L., Chang, Yuh-Shin, Gusella, James F., Hochedlinger, Konrad, Ramesh, Vijaya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596692/ https://www.ncbi.nlm.nih.gov/pubmed/26445504 http://dx.doi.org/10.1371/journal.pone.0140192 |
Ejemplares similares
-
A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas
por: Beauchamp, Roberta L., et al.
Publicado: (2015) -
mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition
por: Beauchamp, Roberta L., et al.
Publicado: (2020) -
Rearranging the chromatin for pluripotency
por: Ferrari, Francesco, et al.
Publicado: (2014) -
Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder
por: Bahl, Samira, et al.
Publicado: (2013) -
Functional Studies of the Yeast Med5, Med15 and Med16 Mediator Tail Subunits
por: Larsson, Miriam, et al.
Publicado: (2013)