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Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport
Mammals obtain nitrogen via the uptake of di- and tri-peptides in the gastrointestinal tract through the action of PepT1 and PepT2, which are members of the POT family of proton-coupled oligopeptide transporters. PepT1 and PepT2 also play an important role in drug transport in the human body. Recent...
Autores principales: | Beale, John H., Parker, Joanne L., Samsudin, Firdaus, Barrett, Anne L., Senan, Anish, Bird, Louise E., Scott, David, Owens, Raymond J., Sansom, Mark S.P., Tucker, Stephen J., Meredith, David, Fowler, Philip W., Newstead, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597091/ https://www.ncbi.nlm.nih.gov/pubmed/26320580 http://dx.doi.org/10.1016/j.str.2015.07.016 |
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