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Evolving Catalytic Properties of the MLL Family SET Domain

Methylation of histone H3 lysine-4 is a hallmark of chromatin associated with active gene expression. The activity of H3K4-specific modification enzymes, in higher eukaryotes the MLL (or KMT2) family, is tightly regulated. The MLL family has six members, each with a specialized function. All contain...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Mittal, Anshumali, Reid, James, Reich, Stephanie, Gamblin, Steven J., Wilson, Jon R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597100/ https://www.ncbi.nlm.nih.gov/pubmed/26320581 http://dx.doi.org/10.1016/j.str.2015.07.018

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