Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart. We show that, during cardiac differentiation, the two transcription factors have partially overlapping expression patterns, with the result that as cardiac pro...

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Detalles Bibliográficos
Autores principales: Dupays, Laurent, Shang, Catherine, Wilson, Robert, Kotecha, Surendra, Wood, Sophie, Towers, Norma, Mohun, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597108/
https://www.ncbi.nlm.nih.gov/pubmed/26411676
http://dx.doi.org/10.1016/j.celrep.2015.08.065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597108/
https://www.ncbi.nlm.nih.gov/pubmed/26411676
http://dx.doi.org/10.1016/j.celrep.2015.08.065

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