Cargando…
Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis
The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart. We show that, during cardiac differentiation, the two transcription factors have partially overlapping expression patterns, with the result that as cardiac pro...
Autores principales: | Dupays, Laurent, Shang, Catherine, Wilson, Robert, Kotecha, Surendra, Wood, Sophie, Towers, Norma, Mohun, Timothy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597108/ https://www.ncbi.nlm.nih.gov/pubmed/26411676 http://dx.doi.org/10.1016/j.celrep.2015.08.065 |
Ejemplares similares
-
Spatiotemporal regulation of enhancers during cardiogenesis
por: Dupays, Laurent, et al.
Publicado: (2016) -
Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function
por: Dupays, Laurent, et al.
Publicado: (2019) -
The Transition from Gastric Intestinal Metaplasia to Gastric Cancer Involves POPDC1 and POPDC3 Downregulation
por: Gingold-Belfer, Rachel, et al.
Publicado: (2021) -
Myeloid Zinc Finger 1 (Mzf1) Differentially Modulates Murine Cardiogenesis by Interacting with an Nkx2.5 Cardiac Enhancer
por: Doppler, Stefanie A., et al.
Publicado: (2014) -
The Role of POPDC Proteins in Cardiac Pacemaking and Conduction
por: Gruscheski, Lena, et al.
Publicado: (2021)