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Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses – Pre-Clinical Evidence and Ongoing Clinical Applications
Radiotherapy (RT) primarily aims to locally destroy the tumor via the induction of DNA damage in the tumor cells. However, the so-called abscopal, namely systemic and immune–mediated, effects of RT move over more and more in the focus of scientists and clinicians since combinations of local irradiat...
Autores principales: | Derer, Anja, Deloch, Lisa, Rubner, Yvonne, Fietkau, Rainer, Frey, Benjamin, Gaipl, Udo S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597129/ https://www.ncbi.nlm.nih.gov/pubmed/26500646 http://dx.doi.org/10.3389/fimmu.2015.00505 |
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