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The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver

Although it is widely accepted that ectopic lipid accumulation in the liver is associated with hepatic insulin resistance, the underlying molecular mechanisms have not been well characterized. Here we employed time resolved quantitative proteomic profiling of mice fed a high fat diet to determine wh...

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Detalles Bibliográficos
Autores principales: Schäfer, Alexander, Neschen, Susanne, Kahle, Melanie, Sarioglu, Hakan, Gaisbauer, Tobias, Imhof, Axel, Adamski, Jerzy, Hauck, Stefanie M., Ueffing, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597150/
https://www.ncbi.nlm.nih.gov/pubmed/26070664
http://dx.doi.org/10.1074/mcp.M115.049064