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The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver
Although it is widely accepted that ectopic lipid accumulation in the liver is associated with hepatic insulin resistance, the underlying molecular mechanisms have not been well characterized. Here we employed time resolved quantitative proteomic profiling of mice fed a high fat diet to determine wh...
Autores principales: | Schäfer, Alexander, Neschen, Susanne, Kahle, Melanie, Sarioglu, Hakan, Gaisbauer, Tobias, Imhof, Axel, Adamski, Jerzy, Hauck, Stefanie M., Ueffing, Marius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597150/ https://www.ncbi.nlm.nih.gov/pubmed/26070664 http://dx.doi.org/10.1074/mcp.M115.049064 |
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