Kaempferol Identified by Zebrafish Assay and Fine Fractionations Strategy from Dysosma versipellis Inhibits Angiogenesis through VEGF and FGF Pathways

Natural products are a rich resource for the discovery of therapeutic substances. By directly using 504 fine fractions from isolated traditional Chinese medicine plants, we performed a transgenic zebrafish based screen for anti-angiogenesis substances. One fraction, DYVE-D3, was found to inhibit the...

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Detalles Bibliográficos
Autores principales: Liang, Fang, Han, Yuxiang, Gao, Hao, Xin, Shengchang, Chen, Shaodan, Wang, Nan, Qin, Wei, Zhong, Hanbing, Lin, Shuo, Yao, Xinsheng, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597183/
https://www.ncbi.nlm.nih.gov/pubmed/26446489
http://dx.doi.org/10.1038/srep14468

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