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Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
The mechanisms by which melanoma and other cancer cells evade anti-tumor immunity remain incompletely understood. Here, we show that the growth of tumors formed by mutant Braf(V600E) mouse melanoma cells in an immunocompetent host requires their production of prostaglandin E2, which suppresses immun...
Autores principales: | Zelenay, Santiago, van der Veen, Annemarthe G., Böttcher, Jan P., Snelgrove, Kathryn J., Rogers, Neil, Acton, Sophie E., Chakravarty, Probir, Girotti, Maria Romina, Marais, Richard, Quezada, Sergio A., Sahai, Erik, Reis e Sousa, Caetano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597191/ https://www.ncbi.nlm.nih.gov/pubmed/26343581 http://dx.doi.org/10.1016/j.cell.2015.08.015 |
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