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KPNB1 mediates PER/CRY nuclear translocation and circadian clock function

Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood. Here, we report that KPNB1, an importin β component of the ncRNA repressor of nuclear fac...

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Detalles Bibliográficos
Autores principales:	Lee, Yool, Jang, A Reum, Francey, Lauren J, Sehgal, Amita, Hogenesch, John B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597257/ https://www.ncbi.nlm.nih.gov/pubmed/26319354 http://dx.doi.org/10.7554/eLife.08647

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