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A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people
BACKGROUND: The percent absorption of lutein from supplements falls well below that from lutein enriched egg yolk, a rich source of phospholipids. Therefore, a supplement of lutein plus phospholipids was tested for effects on serum accumulation. METHODS: A 10 day supplementation with a solid-lipid p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597392/ https://www.ncbi.nlm.nih.gov/pubmed/26445881 http://dx.doi.org/10.1186/s12937-015-0089-x |
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author | DiSilvestro, Robert A. Thomas, Sara Harrison, Earl Epitropoulos, Alice |
author_facet | DiSilvestro, Robert A. Thomas, Sara Harrison, Earl Epitropoulos, Alice |
author_sort | DiSilvestro, Robert A. |
collection | PubMed |
description | BACKGROUND: The percent absorption of lutein from supplements falls well below that from lutein enriched egg yolk, a rich source of phospholipids. Therefore, a supplement of lutein plus phospholipids was tested for effects on serum accumulation. METHODS: A 10 day supplementation with a solid-lipid particle (SLP™) lutein complex or conventional lutein ester was done in apparently healthy people (both supplement types taken with fat containing meals). Plasma lutein was measured pre- and post-supplementation as well as 7 days after supplementation stopped. Changes within each supplement group were analyzed by paired t-test; group comparisons were done by unpaired t-test. RESULTS: The solid-lipid particle complex lutein gave much higher plasma lutein values than conventional lutein ester. The lutein complex showed superior effects based on absolute mean value after 10 days of supplementation, change in value from baseline to 10 days, and value at 7 days after supplement discontinuation. CONCLUSIONS: A solid lipid lutein complex strongly increased plasma lutein levels compared to a conventional form. |
format | Online Article Text |
id | pubmed-4597392 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45973922015-10-08 A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people DiSilvestro, Robert A. Thomas, Sara Harrison, Earl Epitropoulos, Alice Nutr J Research BACKGROUND: The percent absorption of lutein from supplements falls well below that from lutein enriched egg yolk, a rich source of phospholipids. Therefore, a supplement of lutein plus phospholipids was tested for effects on serum accumulation. METHODS: A 10 day supplementation with a solid-lipid particle (SLP™) lutein complex or conventional lutein ester was done in apparently healthy people (both supplement types taken with fat containing meals). Plasma lutein was measured pre- and post-supplementation as well as 7 days after supplementation stopped. Changes within each supplement group were analyzed by paired t-test; group comparisons were done by unpaired t-test. RESULTS: The solid-lipid particle complex lutein gave much higher plasma lutein values than conventional lutein ester. The lutein complex showed superior effects based on absolute mean value after 10 days of supplementation, change in value from baseline to 10 days, and value at 7 days after supplement discontinuation. CONCLUSIONS: A solid lipid lutein complex strongly increased plasma lutein levels compared to a conventional form. BioMed Central 2015-10-07 /pmc/articles/PMC4597392/ /pubmed/26445881 http://dx.doi.org/10.1186/s12937-015-0089-x Text en © DiSilvestro et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research DiSilvestro, Robert A. Thomas, Sara Harrison, Earl Epitropoulos, Alice A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title | A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title_full | A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title_fullStr | A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title_full_unstemmed | A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title_short | A pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
title_sort | pilot comparison of phospolipidated lutein to conventional lutein for effects on plasma lutein concentrations in adult people |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597392/ https://www.ncbi.nlm.nih.gov/pubmed/26445881 http://dx.doi.org/10.1186/s12937-015-0089-x |
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