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Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma

BACKGROUND: Subtelomeric regions dynamically change their epigenetic pattern during development and progression of several malignancies and degenerative disorders. However, DNA methylation of human subtelomeres and their correlation to telomere length (TL) remain undetermined in glioma. RESULTS: Her...

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Detalles Bibliográficos
Autores principales: Choudhury, Samrat Roy, Cui, Yi, Milton, Jacob R., Li, Jian, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597615/
https://www.ncbi.nlm.nih.gov/pubmed/26451167
http://dx.doi.org/10.1186/s13148-015-0140-y