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Vascular Effects of Endothelin Receptor Antagonists Depends on Their Selectivity for ET(A) Versus ET(B) Receptors and on the Functionality of Endothelial ET(B) Receptors

The goal of this study was to characterize the role of Endothelin (ET) type B receptors (ET(B)) on vascular function in healthy and diseased conditions and demonstrate how it affects the pharmacological activity of ET receptor antagonists (ERAs). METHODS: The contribution of the ET(B) receptor to va...

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Detalles Bibliográficos
Autores principales: Iglarz, Marc, Steiner, Pauline, Wanner, Daniel, Rey, Markus, Hess, Patrick, Clozel, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598072/
https://www.ncbi.nlm.nih.gov/pubmed/25992919
http://dx.doi.org/10.1097/FJC.0000000000000283

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