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Vascular Effects of Endothelin Receptor Antagonists Depends on Their Selectivity for ET(A) Versus ET(B) Receptors and on the Functionality of Endothelial ET(B) Receptors
The goal of this study was to characterize the role of Endothelin (ET) type B receptors (ET(B)) on vascular function in healthy and diseased conditions and demonstrate how it affects the pharmacological activity of ET receptor antagonists (ERAs). METHODS: The contribution of the ET(B) receptor to va...
Autores principales: | Iglarz, Marc, Steiner, Pauline, Wanner, Daniel, Rey, Markus, Hess, Patrick, Clozel, Martine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598072/ https://www.ncbi.nlm.nih.gov/pubmed/25992919 http://dx.doi.org/10.1097/FJC.0000000000000283 |
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