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Functional Diversification of Motor Neuron-specific Isl1 Enhancers during Evolution
Functional diversification of motor neurons has occurred in order to selectively control the movements of different body parts including head, trunk and limbs. Here we report that transcription of Isl1, a major gene necessary for motor neuron identity, is controlled by two enhancers, CREST1 (E1) and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598079/ https://www.ncbi.nlm.nih.gov/pubmed/26447474 http://dx.doi.org/10.1371/journal.pgen.1005560 |