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Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells
Human adenovirus has evolved to infect and replicate in terminally differentiated human epithelial cells, predominantly those within the airway, the gut, or the eye. To overcome the block to viral DNA replication present in these cells, the virus expresses the Early 1A proteins (E1A). These immediat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598095/ https://www.ncbi.nlm.nih.gov/pubmed/26448631 http://dx.doi.org/10.1371/journal.pone.0140124 |