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Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells

Human adenovirus has evolved to infect and replicate in terminally differentiated human epithelial cells, predominantly those within the airway, the gut, or the eye. To overcome the block to viral DNA replication present in these cells, the virus expresses the Early 1A proteins (E1A). These immediat...

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Detalles Bibliográficos
Autores principales: Radko, Sandi, Jung, Richard, Olanubi, Oladunni, Pelka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598095/
https://www.ncbi.nlm.nih.gov/pubmed/26448631
http://dx.doi.org/10.1371/journal.pone.0140124