Knockout of Toll-Like Receptors 2 and 4 Prevents Renal Ischemia-Reperfusion-Induced Cardiac Hypertrophy in Mice

We investigated whether the pathways linked to Toll-like receptors 2 and 4 (TLRs) are involved in renal ischemia-reperfusion (I/R)-induced cardiac hypertrophy. Wild type (WT) C57BL/6J, TLR2(-/-) and TLR4(-/-) mice were subjected to left kidney ischemia for 60 min followed by reperfusion for 5, 8, 12...

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Detalles Bibliográficos
Autores principales: Trentin-Sonoda, Mayra, da Silva, Rogério Cirino, Kmit, Fernanda Vieira, Abrahão, Mariana Vieira, Monnerat Cahli, Gustavo, Brasil, Guilherme Visconde, Muzi-Filho, Humberto, Silva, Paulo André, Tovar-Moll, Fernanda Freire, Vieyra, Adalberto, Medei, Emiliano, Carneiro-Ramos, Marcela Sorelli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598103/
https://www.ncbi.nlm.nih.gov/pubmed/26448184
http://dx.doi.org/10.1371/journal.pone.0139350

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