Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model

We have previously shown that mitochondria-targeted vitamin E (Mito-Vit-E), a mtROS specific antioxidant, improves cardiac performance and attenuates inflammation in a pneumonia-related sepsis model. In this study, we applied the same approaches to decipher the signaling pathway(s) of mtROS-dependen...

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Detalles Bibliográficos
Autores principales: Yao, Xiao, Carlson, Deborah, Sun, Yuxiao, Ma, Lisha, Wolf, Steven E., Minei, Joseph P., Zang, Qun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598156/
https://www.ncbi.nlm.nih.gov/pubmed/26448624
http://dx.doi.org/10.1371/journal.pone.0139416

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