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Oscillation of p38 activity controls efficient pro-inflammatory gene expression

The p38 MAP kinase signalling pathway controls inflammatory responses and is an important target of anti-inflammatory drugs. Although pro-inflammatory cytokines such as interleukin-1β (IL-1β) appear to induce only transient activation of p38 (over ∼60 min), longer cytokine exposure is necessary to i...

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Detalles Bibliográficos
Autores principales: Tomida, Taichiro, Takekawa, Mutsuhiro, Saito, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598561/
https://www.ncbi.nlm.nih.gov/pubmed/26399197
http://dx.doi.org/10.1038/ncomms9350

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