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Atomic-level characterization of transport cycle thermodynamics in the glycerol-3-phosphate:phosphate antiporter

Membrane transporters actively translocate their substrate by undergoing large-scale structural transitions between inward- (IF) and outward-facing (OF) states (‘alternating-access' mechanism). Despite extensive structural studies, atomic-level mechanistic details of such structural transitions...

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Detalles Bibliográficos
Autores principales:	Moradi, Mahmoud, Enkavi, Giray, Tajkhorshid, Emad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598623/ https://www.ncbi.nlm.nih.gov/pubmed/26417850 http://dx.doi.org/10.1038/ncomms9393

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