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An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products
Bacterial natural products are a diverse and valuable group of small molecules, and genome sequencing indicates that the vast majority remain undiscovered. The prediction of natural product structures from biosynthetic assembly lines can facilitate their discovery, but highly automated, accurate, an...
Autores principales: | Johnston, Chad W., Skinnider, Michael A., Wyatt, Morgan A., Li, Xiang, Ranieri, Michael R. M., Yang, Lian, Zechel, David L., Ma, Bin, Magarvey, Nathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598715/ https://www.ncbi.nlm.nih.gov/pubmed/26412281 http://dx.doi.org/10.1038/ncomms9421 |
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