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CPI motif interaction is necessary for capping protein function in cells
Capping protein (CP) has critical roles in actin assembly in vivo and in vitro. CP binds with high affinity to the barbed end of actin filaments, blocking the addition and loss of actin subunits. Heretofore, models for actin assembly in cells generally assumed that CP is constitutively active, diffu...
Autores principales: | Edwards, Marc, McConnell, Patrick, Schafer, Dorothy A., Cooper, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598739/ https://www.ncbi.nlm.nih.gov/pubmed/26412145 http://dx.doi.org/10.1038/ncomms9415 |
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