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The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease

DIS3 is a conserved exoribonuclease and catalytic subunit of the exosome, a protein complex involved in the 3' to 5' degradation and processing of both nuclear and cytoplasmic RNA species. Recently, aberrant expression of DIS3 has been found to be implicated in a range of different cancers...

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Detalles Bibliográficos
Autores principales:	Robinson, Sophie R., Oliver, Antony W., Chevassut, Timothy J., Newbury, Sarah F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598762/ https://www.ncbi.nlm.nih.gov/pubmed/26193331 http://dx.doi.org/10.3390/biom5031515

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