Cargando…
Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process
Alternative pre-messenger RNA splicing in higher plants emerges as an important layer of regulation upon exposure to exogenous and endogenous cues. Accordingly, mutants defective in RNA-binding proteins predicted to function in the splicing process show severe phenotypic alterations. Among those are...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598772/ https://www.ncbi.nlm.nih.gov/pubmed/26213982 http://dx.doi.org/10.3390/biom5031717 |
_version_ | 1782394128565272576 |
---|---|
author | Meyer, Katja Koester, Tino Staiger, Dorothee |
author_facet | Meyer, Katja Koester, Tino Staiger, Dorothee |
author_sort | Meyer, Katja |
collection | PubMed |
description | Alternative pre-messenger RNA splicing in higher plants emerges as an important layer of regulation upon exposure to exogenous and endogenous cues. Accordingly, mutants defective in RNA-binding proteins predicted to function in the splicing process show severe phenotypic alterations. Among those are developmental defects, impaired responses to pathogen threat or abiotic stress factors, and misregulation of the circadian timing system. A suite of splicing factors has been identified in the model plant Arabidopsis thaliana. Here we summarize recent insights on how defects in these splicing factors impair plant performance. |
format | Online Article Text |
id | pubmed-4598772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-45987722015-10-15 Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process Meyer, Katja Koester, Tino Staiger, Dorothee Biomolecules Review Alternative pre-messenger RNA splicing in higher plants emerges as an important layer of regulation upon exposure to exogenous and endogenous cues. Accordingly, mutants defective in RNA-binding proteins predicted to function in the splicing process show severe phenotypic alterations. Among those are developmental defects, impaired responses to pathogen threat or abiotic stress factors, and misregulation of the circadian timing system. A suite of splicing factors has been identified in the model plant Arabidopsis thaliana. Here we summarize recent insights on how defects in these splicing factors impair plant performance. MDPI 2015-07-24 /pmc/articles/PMC4598772/ /pubmed/26213982 http://dx.doi.org/10.3390/biom5031717 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Meyer, Katja Koester, Tino Staiger, Dorothee Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title | Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title_full | Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title_fullStr | Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title_full_unstemmed | Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title_short | Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process |
title_sort | pre-mrna splicing in plants: in vivo functions of rna-binding proteins implicated in the splicing process |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598772/ https://www.ncbi.nlm.nih.gov/pubmed/26213982 http://dx.doi.org/10.3390/biom5031717 |
work_keys_str_mv | AT meyerkatja premrnasplicinginplantsinvivofunctionsofrnabindingproteinsimplicatedinthesplicingprocess AT koestertino premrnasplicinginplantsinvivofunctionsofrnabindingproteinsimplicatedinthesplicingprocess AT staigerdorothee premrnasplicinginplantsinvivofunctionsofrnabindingproteinsimplicatedinthesplicingprocess |