Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement

[Image: see text] Particle and domain sizes strongly influence the properties of materials. Here we present an NMR approach based on paramagnetic relaxation enhancement (PRE) relayed by spin diffusion (SD), which allows us to determine lengths in the nm−μm range. We demonstrate the method on multico...

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Autores principales: Schlagnitweit, Judith, Tang, Mingxue, Baias, Maria, Richardson, Sara, Schantz, Staffan, Emsley, Lyndon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598824/
https://www.ncbi.nlm.nih.gov/pubmed/26397956
http://dx.doi.org/10.1021/jacs.5b08249
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author Schlagnitweit, Judith
Tang, Mingxue
Baias, Maria
Richardson, Sara
Schantz, Staffan
Emsley, Lyndon
author_facet Schlagnitweit, Judith
Tang, Mingxue
Baias, Maria
Richardson, Sara
Schantz, Staffan
Emsley, Lyndon
author_sort Schlagnitweit, Judith
collection PubMed
description [Image: see text] Particle and domain sizes strongly influence the properties of materials. Here we present an NMR approach based on paramagnetic relaxation enhancement (PRE) relayed by spin diffusion (SD), which allows us to determine lengths in the nm−μm range. We demonstrate the method on multicomponent organic polymer mixtures by selectively doping one component with a paramagnetic center in order to measure the domain size in a second component. Using this approach we determine domain sizes in ethyl cellulose/hydroxypropyl cellulose film coatings in pharmaceutical controlled release formulations. Here we measure particle sizes ranging from around 50 to 200 nm.
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spelling pubmed-45988242015-10-14 Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement Schlagnitweit, Judith Tang, Mingxue Baias, Maria Richardson, Sara Schantz, Staffan Emsley, Lyndon J Am Chem Soc [Image: see text] Particle and domain sizes strongly influence the properties of materials. Here we present an NMR approach based on paramagnetic relaxation enhancement (PRE) relayed by spin diffusion (SD), which allows us to determine lengths in the nm−μm range. We demonstrate the method on multicomponent organic polymer mixtures by selectively doping one component with a paramagnetic center in order to measure the domain size in a second component. Using this approach we determine domain sizes in ethyl cellulose/hydroxypropyl cellulose film coatings in pharmaceutical controlled release formulations. Here we measure particle sizes ranging from around 50 to 200 nm. American Chemical Society 2015-09-23 2015-10-07 /pmc/articles/PMC4598824/ /pubmed/26397956 http://dx.doi.org/10.1021/jacs.5b08249 Text en Copyright © 2015 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Schlagnitweit, Judith
Tang, Mingxue
Baias, Maria
Richardson, Sara
Schantz, Staffan
Emsley, Lyndon
Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title_full Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title_fullStr Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title_full_unstemmed Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title_short Nanostructure of Materials Determined by Relayed Paramagnetic Relaxation Enhancement
title_sort nanostructure of materials determined by relayed paramagnetic relaxation enhancement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598824/
https://www.ncbi.nlm.nih.gov/pubmed/26397956
http://dx.doi.org/10.1021/jacs.5b08249
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AT baiasmaria nanostructureofmaterialsdeterminedbyrelayedparamagneticrelaxationenhancement
AT richardsonsara nanostructureofmaterialsdeterminedbyrelayedparamagneticrelaxationenhancement
AT schantzstaffan nanostructureofmaterialsdeterminedbyrelayedparamagneticrelaxationenhancement
AT emsleylyndon nanostructureofmaterialsdeterminedbyrelayedparamagneticrelaxationenhancement

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