Exchanging ligand-binding specificity between a pair of mouse olfactory receptor paralogs reveals odorant recognition principles

A multi-gene family of ~1000 G protein-coupled olfactory receptors (ORs) constitutes the molecular basis of mammalian olfaction. Due to the lack of structural data its remarkable capacity to detect and discriminate thousands of odorants remains poorly understood on the structural level of the recept...

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Detalles Bibliográficos
Autores principales: Baud, Olivia, Yuan, Shuguang, Veya, Luc, Filipek, Slawomir, Vogel, Horst, Pick, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598832/
https://www.ncbi.nlm.nih.gov/pubmed/26449412
http://dx.doi.org/10.1038/srep14948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598832/
https://www.ncbi.nlm.nih.gov/pubmed/26449412
http://dx.doi.org/10.1038/srep14948

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