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Exchanging ligand-binding specificity between a pair of mouse olfactory receptor paralogs reveals odorant recognition principles
A multi-gene family of ~1000 G protein-coupled olfactory receptors (ORs) constitutes the molecular basis of mammalian olfaction. Due to the lack of structural data its remarkable capacity to detect and discriminate thousands of odorants remains poorly understood on the structural level of the recept...
Autores principales: | Baud, Olivia, Yuan, Shuguang, Veya, Luc, Filipek, Slawomir, Vogel, Horst, Pick, Horst |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598832/ https://www.ncbi.nlm.nih.gov/pubmed/26449412 http://dx.doi.org/10.1038/srep14948 |
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