O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth

The pentose phosphate pathway (PPP) plays a critical role in macromolecule biosynthesis and maintaining cellular redox homoeostasis in rapidly proliferating cells. Upregulation of the PPP has been shown in several types of cancer. However, how the PPP is regulated to confer a selective growth advant...

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Detalles Bibliográficos
Autores principales: Rao, Xiongjian, Duan, Xiaotao, Mao, Weimin, Li, Xuexia, Li, Zhonghua, Li, Qian, Zheng, Zhiguo, Xu, Haimiao, Chen, Min, Wang, Peng G., Wang, Yingjie, Shen, Binghui, Yi, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598839/
https://www.ncbi.nlm.nih.gov/pubmed/26399441
http://dx.doi.org/10.1038/ncomms9468

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