CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis

The complement system is important for the host defence against infection as well as for the development of inflammatory diseases. Here we show that C1q/TNF-related protein 6 (CTRP6; gene symbol C1qtnf6) expression is elevated in mouse rheumatoid arthritis (RA) models. C1qtnf6(−/−) mice are highly s...

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Detalles Bibliográficos
Autores principales: Murayama, Masanori A., Kakuta, Shigeru, Inoue, Asuka, Umeda, Naoto, Yonezawa, Tomo, Maruhashi, Takumi, Tateishi, Koichiro, Ishigame, Harumichi, Yabe, Rikio, Ikeda, Satoshi, Seno, Akimasa, Chi, Hsi-Hua, Hashiguchi, Yuriko, Kurata, Riho, Tada, Takuya, Kubo, Sachiko, Sato, Nozomi, Liu, Yang, Hattori, Masahira, Saijo, Shinobu, Matsushita, Misao, Fujita, Teizo, Sumida, Takayuki, Iwakura, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598845/
https://www.ncbi.nlm.nih.gov/pubmed/26404464
http://dx.doi.org/10.1038/ncomms9483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598845/
https://www.ncbi.nlm.nih.gov/pubmed/26404464
http://dx.doi.org/10.1038/ncomms9483

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