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CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis
The complement system is important for the host defence against infection as well as for the development of inflammatory diseases. Here we show that C1q/TNF-related protein 6 (CTRP6; gene symbol C1qtnf6) expression is elevated in mouse rheumatoid arthritis (RA) models. C1qtnf6(−/−) mice are highly s...
Autores principales: | Murayama, Masanori A., Kakuta, Shigeru, Inoue, Asuka, Umeda, Naoto, Yonezawa, Tomo, Maruhashi, Takumi, Tateishi, Koichiro, Ishigame, Harumichi, Yabe, Rikio, Ikeda, Satoshi, Seno, Akimasa, Chi, Hsi-Hua, Hashiguchi, Yuriko, Kurata, Riho, Tada, Takuya, Kubo, Sachiko, Sato, Nozomi, Liu, Yang, Hattori, Masahira, Saijo, Shinobu, Matsushita, Misao, Fujita, Teizo, Sumida, Takayuki, Iwakura, Yoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598845/ https://www.ncbi.nlm.nih.gov/pubmed/26404464 http://dx.doi.org/10.1038/ncomms9483 |
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