Cargando…
Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells
H5N1 influenza A virus (IAV) causes severe respiratory diseases and high mortality rates in animals and humans. MicroRNAs are being increasingly studied to evaluate their potential as therapeutic entities to combat viral infection. However, mechanistic studies delineating the roles of microRNAs in r...
Autores principales: | Zhao, Lianzhong, Zhu, Jiping, Zhou, Hongbo, Zhao, Zongzheng, Zou, Zhong, Liu, Xiaokun, Lin, Xian, Zhang, Xue, Deng, Xuexia, Wang, Ruifang, Chen, Huanchun, Jin, Meilin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598873/ https://www.ncbi.nlm.nih.gov/pubmed/26450567 http://dx.doi.org/10.1038/srep14991 |
Ejemplares similares
-
The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2
por: Zhao, Lianzhong, et al.
Publicado: (2019) -
The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression
por: Lin, Xian, et al.
Publicado: (2016) -
Pigeon RIG-I Function in Innate Immunity against H9N2 IAV and IBDV
por: Xu, Wenping, et al.
Publicado: (2015) -
A Novel lncRNA SAAL Suppresses IAV Replication by Promoting Innate Responses
por: Liu, Qingzheng, et al.
Publicado: (2022) -
HIST1H1C Regulates Interferon-β and Inhibits Influenza Virus Replication by Interacting with IRF3
por: Liu, Xiaokun, et al.
Publicado: (2017)