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Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial
BACKGROUND: The main goals in treating burns are to accelerate tissue renovation and prevent infection. Topical antibiotics are used in the treatment of burns, but they can cause side effects. Recently, a traditional ointment (Olea) has been used in Iran in the treatment of burns. This study examine...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598908/ https://www.ncbi.nlm.nih.gov/pubmed/26457099 http://dx.doi.org/10.4103/1735-9066.164507 |
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author | Zahmatkesh, Mohsen Manesh, Mohammad Jalili Babashahabi, Ronak |
author_facet | Zahmatkesh, Mohsen Manesh, Mohammad Jalili Babashahabi, Ronak |
author_sort | Zahmatkesh, Mohsen |
collection | PubMed |
description | BACKGROUND: The main goals in treating burns are to accelerate tissue renovation and prevent infection. Topical antibiotics are used in the treatment of burns, but they can cause side effects. Recently, a traditional ointment (Olea) has been used in Iran in the treatment of burns. This study examines the effect of topical honey ointment in healing of burn patients. MATERIALS AND METHODS: In this randomized controlled trial (RCT), 30 hospitalized patients selected by conventional sampling (10 in Olea group and 20 in Acetate Mafenide ointment group) were evaluated. Inclusion criteria were: having second-degree burns and body surface area equal to or < 40%. One group was treated using topical Olea ointment and the other with Acetate Mafenide ointment (8.5%). Chi-square, Fisher exact test, and Kaplan–Meier were used. Significance level was considered as P < 0.05. RESULTS: None of the patients in the Olea group needed surgery for debridement, while in the second group, 13 patients (65%) needed debridement (P = 0.001). In the Olea group, 1 patient (10%) and in the second group, 19 patients (95%) had positive cultures after 7 days (P < 0.001). The mean time of granulation tissue formation in the Olea group was 12 days (10.3–13.6) and in the other group, it was 17 days (13.3–20.6) (P < 0.001). CONCLUSIONS: Olea ointment is a useful treatment for burns, and it can prevent infections, accelerate tissue repair, and facilitate debridement. Therefore, using this ointment is recommended for the treatment of burns. |
format | Online Article Text |
id | pubmed-4598908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-45989082015-10-09 Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial Zahmatkesh, Mohsen Manesh, Mohammad Jalili Babashahabi, Ronak Iran J Nurs Midwifery Res Original Article BACKGROUND: The main goals in treating burns are to accelerate tissue renovation and prevent infection. Topical antibiotics are used in the treatment of burns, but they can cause side effects. Recently, a traditional ointment (Olea) has been used in Iran in the treatment of burns. This study examines the effect of topical honey ointment in healing of burn patients. MATERIALS AND METHODS: In this randomized controlled trial (RCT), 30 hospitalized patients selected by conventional sampling (10 in Olea group and 20 in Acetate Mafenide ointment group) were evaluated. Inclusion criteria were: having second-degree burns and body surface area equal to or < 40%. One group was treated using topical Olea ointment and the other with Acetate Mafenide ointment (8.5%). Chi-square, Fisher exact test, and Kaplan–Meier were used. Significance level was considered as P < 0.05. RESULTS: None of the patients in the Olea group needed surgery for debridement, while in the second group, 13 patients (65%) needed debridement (P = 0.001). In the Olea group, 1 patient (10%) and in the second group, 19 patients (95%) had positive cultures after 7 days (P < 0.001). The mean time of granulation tissue formation in the Olea group was 12 days (10.3–13.6) and in the other group, it was 17 days (13.3–20.6) (P < 0.001). CONCLUSIONS: Olea ointment is a useful treatment for burns, and it can prevent infections, accelerate tissue repair, and facilitate debridement. Therefore, using this ointment is recommended for the treatment of burns. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4598908/ /pubmed/26457099 http://dx.doi.org/10.4103/1735-9066.164507 Text en Copyright: © Iranian Journal of Nursing and Midwifery Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms |
spellingShingle | Original Article Zahmatkesh, Mohsen Manesh, Mohammad Jalili Babashahabi, Ronak Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title | Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title_full | Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title_fullStr | Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title_full_unstemmed | Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title_short | Effect of Olea ointment and Acetate Mafenide on burn wounds – A randomized clinical trial |
title_sort | effect of olea ointment and acetate mafenide on burn wounds – a randomized clinical trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598908/ https://www.ncbi.nlm.nih.gov/pubmed/26457099 http://dx.doi.org/10.4103/1735-9066.164507 |
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