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Pseudoepitheliomatous hyperplasia after diode laser oral surgery. An experimental study
BACKGROUND: To examine the process of epithelial reparation in a surgical wound caused by diode laser. MATERIAL AND METHODS: An experimental study with 27 Sprage-Dawley rats was undertaken. The animals were randomly allocated to two experimental groups, whose individuals underwent glossectomy by mea...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598923/ https://www.ncbi.nlm.nih.gov/pubmed/26116841 http://dx.doi.org/10.4317/medoral.20519 |
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author | Seoane, Juan González-Mosquera, Antonio García-Martín, José-Manuel García-Caballero, Lucía Seoane-Romero, Juan-Manuel Varela-Centelles, Pablo |
author_facet | Seoane, Juan González-Mosquera, Antonio García-Martín, José-Manuel García-Caballero, Lucía Seoane-Romero, Juan-Manuel Varela-Centelles, Pablo |
author_sort | Seoane, Juan |
collection | PubMed |
description | BACKGROUND: To examine the process of epithelial reparation in a surgical wound caused by diode laser. MATERIAL AND METHODS: An experimental study with 27 Sprage-Dawley rats was undertaken. The animals were randomly allocated to two experimental groups, whose individuals underwent glossectomy by means of a diode laser at different wattages, and a control group treated using a number 15 scalpel blade. The animals were slaughtered at the 2nd, 7th, and 14th day after glossectomy. The specimens were independently studied by two pathologists (blinded for the specimens’ group). RESULTS: At the 7th day, re-epithelisation was slightly faster for the control group (conventional scalpel) (p=0.011). At the 14th day, complete re-epithelization was observed for all groups. The experimental groups displayed a pseudoepitheliomatous hyperplasia. CONCLUSIONS: It is concluded that, considering the limitations of this kind of experimental studies, early re-epithelisation occurs slightly faster when a conventional scalpel is used for incision, although re-epithelisation is completed in two weeks no matter the instrument used. In addition, pseudoepitheliomatous hyperplasia is a potential event after oral mucosa surgery with diode laser. Knowledge about this phenomenon (not previously described) may prevent diagnostic mistakes and inadequate treatment approaches, particularly when dealing with potentially malignant oral lesions. Key words:Diode laser, animal model, oral biopsy, oral cancer, oral precancer, pseudoepitheliomatous hyperplasia. |
format | Online Article Text |
id | pubmed-4598923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-45989232015-10-15 Pseudoepitheliomatous hyperplasia after diode laser oral surgery. An experimental study Seoane, Juan González-Mosquera, Antonio García-Martín, José-Manuel García-Caballero, Lucía Seoane-Romero, Juan-Manuel Varela-Centelles, Pablo Med Oral Patol Oral Cir Bucal Research BACKGROUND: To examine the process of epithelial reparation in a surgical wound caused by diode laser. MATERIAL AND METHODS: An experimental study with 27 Sprage-Dawley rats was undertaken. The animals were randomly allocated to two experimental groups, whose individuals underwent glossectomy by means of a diode laser at different wattages, and a control group treated using a number 15 scalpel blade. The animals were slaughtered at the 2nd, 7th, and 14th day after glossectomy. The specimens were independently studied by two pathologists (blinded for the specimens’ group). RESULTS: At the 7th day, re-epithelisation was slightly faster for the control group (conventional scalpel) (p=0.011). At the 14th day, complete re-epithelization was observed for all groups. The experimental groups displayed a pseudoepitheliomatous hyperplasia. CONCLUSIONS: It is concluded that, considering the limitations of this kind of experimental studies, early re-epithelisation occurs slightly faster when a conventional scalpel is used for incision, although re-epithelisation is completed in two weeks no matter the instrument used. In addition, pseudoepitheliomatous hyperplasia is a potential event after oral mucosa surgery with diode laser. Knowledge about this phenomenon (not previously described) may prevent diagnostic mistakes and inadequate treatment approaches, particularly when dealing with potentially malignant oral lesions. Key words:Diode laser, animal model, oral biopsy, oral cancer, oral precancer, pseudoepitheliomatous hyperplasia. Medicina Oral S.L. 2015-09 2015-06-27 /pmc/articles/PMC4598923/ /pubmed/26116841 http://dx.doi.org/10.4317/medoral.20519 Text en Copyright: © 2015 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Seoane, Juan González-Mosquera, Antonio García-Martín, José-Manuel García-Caballero, Lucía Seoane-Romero, Juan-Manuel Varela-Centelles, Pablo Pseudoepitheliomatous hyperplasia after diode laser oral surgery. An experimental study |
title | Pseudoepitheliomatous hyperplasia after diode laser
oral surgery. An experimental study |
title_full | Pseudoepitheliomatous hyperplasia after diode laser
oral surgery. An experimental study |
title_fullStr | Pseudoepitheliomatous hyperplasia after diode laser
oral surgery. An experimental study |
title_full_unstemmed | Pseudoepitheliomatous hyperplasia after diode laser
oral surgery. An experimental study |
title_short | Pseudoepitheliomatous hyperplasia after diode laser
oral surgery. An experimental study |
title_sort | pseudoepitheliomatous hyperplasia after diode laser
oral surgery. an experimental study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598923/ https://www.ncbi.nlm.nih.gov/pubmed/26116841 http://dx.doi.org/10.4317/medoral.20519 |
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