Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review

Malignant pericardial effusion (MPCE) is a common complication of advanced malignant tumors, and interferes severely with patient prognosis and quality of life. The standard treatment for this complication is intracavitary perfusion of chemotherapeutic drugs, which is limited by unsatisfactory thera...

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Autores principales: Chen, Dawei, Zhang, Yan, Shi, Fang, Li, Minghuan, Zhu, Hui, Kong, Li, Yu, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599051/
https://www.ncbi.nlm.nih.gov/pubmed/26491350
http://dx.doi.org/10.2147/OTT.S90145
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author Chen, Dawei
Zhang, Yan
Shi, Fang
Li, Minghuan
Zhu, Hui
Kong, Li
Yu, Jinming
author_facet Chen, Dawei
Zhang, Yan
Shi, Fang
Li, Minghuan
Zhu, Hui
Kong, Li
Yu, Jinming
author_sort Chen, Dawei
collection PubMed
description Malignant pericardial effusion (MPCE) is a common complication of advanced malignant tumors, and interferes severely with patient prognosis and quality of life. The standard treatment for this complication is intracavitary perfusion of chemotherapeutic drugs, which is limited by unsatisfactory therapeutic effects and serious adverse events. We report a patient with MPCE who was treated with bevacizumab by pericardial perfusion, resulting in a complete response. This case supports the use of intrapericardial bevacizumab as a potential treatment for MPCE.
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spelling pubmed-45990512015-10-21 Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review Chen, Dawei Zhang, Yan Shi, Fang Li, Minghuan Zhu, Hui Kong, Li Yu, Jinming Onco Targets Ther Case Report Malignant pericardial effusion (MPCE) is a common complication of advanced malignant tumors, and interferes severely with patient prognosis and quality of life. The standard treatment for this complication is intracavitary perfusion of chemotherapeutic drugs, which is limited by unsatisfactory therapeutic effects and serious adverse events. We report a patient with MPCE who was treated with bevacizumab by pericardial perfusion, resulting in a complete response. This case supports the use of intrapericardial bevacizumab as a potential treatment for MPCE. Dove Medical Press 2015-10-01 /pmc/articles/PMC4599051/ /pubmed/26491350 http://dx.doi.org/10.2147/OTT.S90145 Text en © 2015 Chen et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Chen, Dawei
Zhang, Yan
Shi, Fang
Li, Minghuan
Zhu, Hui
Kong, Li
Yu, Jinming
Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title_full Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title_fullStr Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title_full_unstemmed Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title_short Sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
title_sort sustained response of malignant pericardial effusion to intrapericardial bevacizumab in an advanced lung cancer patient: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599051/
https://www.ncbi.nlm.nih.gov/pubmed/26491350
http://dx.doi.org/10.2147/OTT.S90145
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