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Regulation of MT1-MMP/MMP-2/TIMP-2 axis in human placenta

Matrix metalloproteinases (MMPs) and specific endogenous tissue inhibitors of metalloproteinases (TIMPs) mediate rupture of the fetal membranes in both physiological and pathological conditions. MMPs and TIMPs are subject to regulation by DNA methylation in human malignancies and pre-eclampsia. To d...

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Detalles Bibliográficos
Autores principales: Vincent, Zoë L, Mitchell, Murray D, Ponnampalam, Anna P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599070/
https://www.ncbi.nlm.nih.gov/pubmed/26491367
http://dx.doi.org/10.2147/JIR.S88039