Cargando…

Evaluation of the antidepressant-like effects of acute and sub-acute administration of crocin and crocetin in mice

OBJECTIVE: The present study was designed to investigate the putative antidepressant effects of crocin and crocetin, two major active ingredients of Crocus sativus L. (saffron) using mice in two different regimens of acute and sub-acute administration. MATERIAL AND METHODS: In acute treatment, antid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amin, Bahareh, Nakhsaz, Alireza, Hosseinzadeh, Hossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599114/ https://www.ncbi.nlm.nih.gov/pubmed/26468466

Ejemplares similares

Comparative Evaluation of Hepatoprotective Activities of Geniposide, Crocins and Crocetin by CCl(4)-Induced liver Injury in Mice
por: Chen, Ping, et al.
Publicado: (2016)

The Prophylactic and Therapeutic Effects of Saffron Extract and Crocin on Ethanol Withdrawal Syndrome in Mice
por: Shoja, Maryam, et al.
Publicado: (2018)

Effects of Intestinal Microbiota on Pharmacokinetics of Crocin and Crocetin in Male Sprague-Dawley Rats
por: Shakya, Rajina, et al.
Publicado: (2020)

Changes of Crocin and Other Crocetin Glycosides in Saffron Through Cooking Models, and Discovery of Rare Crocetin Glycosides in the Yellow Flowers of Freesia Hybrida
por: Shindo, Kazutoshi, et al.
Publicado: (2022)

Crocin Prevents Sub-Cellular Organelle Damage, Proteolysis and Apoptosis in Rat Hepatocytes: A Justification for Its Hepatoprotection
por: Yousefsani, Bahareh Sadat, et al.
Publicado: (2018)

Crocetin and crocin decreased cholesterol and triglyceride content of both breast cancer tumors and cell lines
por: Hashemi, Seyed Ali, et al.
Publicado: (2020)

Antidepressant Effect of Crocin in Mice with Chronic Mild Stress
por: Alsanie, Walaa F., et al.
Publicado: (2022)

Crocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats
por: Razavi, Marjan, et al.
Publicado: (2013)

Comparative Study on The Preventive Effect of Saffron Carotenoids, Crocin and Crocetin, in NMU-Induced Breast Cancer in Rats
por: Sajjadi, Meysam, et al.
Publicado: (2017)

Study of the Role of CREB, BDNF, and VGF Neuropeptide in Long Term Antidepressant Activity of Crocin in the Rat Cerebellum
por: Razavi, Bibi Marjan, et al.
Publicado: (2017)

Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
por: Vahdati Hassani, Faezeh, et al.
Publicado: (2014)

Protective effect of crocin against d-galactose-induced aging in mice
por: Mohammadi, Elaheh, et al.
Publicado: (2018)

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
por: Zhang, Yue, et al.
Publicado: (2019)

Protective Effect of Crocin against Mitochondrial Damage and Memory Deficit Induced by Beta-amyloid in the Hippocampus of Rats
por: Yousefsani, Bahareh Sadat, et al.
Publicado: (2021)

The effects of tramadol administration on hippocampal cell apoptosis, learning and memory in adult rats and neuroprotective effects of crocin
por: Baghishani, Farideh, et al.
Publicado: (2018)

Proteomic screening of molecular targets of crocin
por: Hosseinzadeh, Hossein, et al.
Publicado: (2014)

Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers
por: Mohamadpour, Amir Houshang, et al.
Publicado: (2013)

Evaluation of possible effects of crocin against nitrate tolerance and endothelial dysfunction
por: Omidkhoda, Seyedeh Farzaneh, et al.
Publicado: (2020)

Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells
por: Rajabian, Fatemeh, et al.
Publicado: (2023)

Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies
por: Rezaee-Khorasany, Alireza, et al.
Publicado: (2020)

Crocin reduced acrylamide-induced neurotoxicity in Wistar rat through inhibition of oxidative stress
por: Mehri, Soghra, et al.
Publicado: (2015)

The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Models
por: Chalatsa, Ioanna, et al.
Publicado: (2019)

Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples
por: Mohammadpour, Amir Hooshang, et al.
Publicado: (2013)

Development and Evaluation of Crocetin-Functionalized Pegylated Magnetite Nanoparticles for Hepatocellular Carcinoma
por: Ibrahim, Sulafa, et al.
Publicado: (2023)

Crocetin: A Systematic Review
por: Guo, Zi-Liang, et al.
Publicado: (2022)

The mechanism of acute fasting‐induced antidepressant‐like effects in mice
por: Cui, Ranji, et al.
Publicado: (2017)

Study on Antidepressant Effect and Mechanism of Crocin Mediated by the mTOR Signaling Pathway
por: Wang, Yan, et al.
Publicado: (2022)

Enhancement of Antinociceptive Effect by Co-administration of Amitriptyline and Crocus Sativus in a Rat Model of Neuropathic Pain
por: Amin, Bahareh, et al.
Publicado: (2017)

Protective Effects of Crocin Against Hepatic Damages in D-galactose Aging Model in Rats
por: Omidkhoda, Seyedeh Farzaneh, et al.
Publicado: (2020)

Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism
por: Kamyar, Marzyeh, et al.
Publicado: (2016)

Memory enhancement and protective effects of crocin against D-galactose aging model in the hippocampus of Wistar rats
por: Heidari, Somaye, et al.
Publicado: (2017)

Oral administration of inosine produces antidepressant-like effects in mice
por: Muto, Junko, et al.
Publicado: (2014)

Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension
por: Llorens, Silvia, et al.
Publicado: (2015)

Involvement of brain-derived neurotrophic factor (BDNF) on malathion induced depressive-like behavior in subacute exposure and protective effects of crocin
por: Dorri, Somaye Ardebili, et al.
Publicado: (2015)

Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
por: Imenshahidi, Mohsen, et al.
Publicado: (2014)

Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice
por: Song, Yinghua, et al.
Publicado: (2013)

Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice
por: Zhang, Jin, et al.
Publicado: (2018)

Comparing the Therapeutic Effects of Crocin, Escitalopram and Co-Administration of Escitalopram and Crocin on Learning and Memory in Rats with Stress-Induced Depression
por: Joodaki, Mehran, et al.
Publicado: (2021)

Effect of crocin on nitric oxide synthase expression in post-ischemic isolated rat heart
por: Esmaeilizadeh, Mahdi, et al.
Publicado: (2015)

The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice
por: Estrada-Reyes, Rosa, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t898lst7rdocp4o62hu3lse9d4