Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer

BACKGROUND: Keratins are intermediate filament (IF) proteins, which form part of the epithelial cytoskeleton and which have been implicated pathology of inflammatory bowel diseases (IBD). METHODS: In this study biopsies were obtained from IBD patients grouped by disease duration and subtype into eig...

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Detalles Bibliográficos
Autores principales: Corfe, Bernard M, Majumdar, Debabrata, Assadsangabi, Arash, Marsh, Alexandra M R, Cross, Simon S, Connolly, Joanne B, Evans, Caroline A, Lobo, Alan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599170/
https://www.ncbi.nlm.nih.gov/pubmed/26462276
http://dx.doi.org/10.1136/bmjgast-2014-000024

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