Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

A response to ‘Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data’ by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D in Genome Biology, 2013, 14:R95 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaobei, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599205/
https://www.ncbi.nlm.nih.gov/pubmed/26450178
http://dx.doi.org/10.1186/s13059-015-0781-3
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author Zhou, Xiaobei
Robinson, Mark D.
author_facet Zhou, Xiaobei
Robinson, Mark D.
author_sort Zhou, Xiaobei
collection PubMed
description A response to ‘Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data’ by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D in Genome Biology, 2013, 14:R95 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-015-0781-3) contains supplementary material, which is available to authorized users.
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spelling pubmed-45992052015-10-10 Do count-based differential expression methods perform poorly when genes are expressed in only one condition? Zhou, Xiaobei Robinson, Mark D. Genome Biol Correspondence A response to ‘Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data’ by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D in Genome Biology, 2013, 14:R95 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-015-0781-3) contains supplementary material, which is available to authorized users. BioMed Central 2015-10-08 2015 /pmc/articles/PMC4599205/ /pubmed/26450178 http://dx.doi.org/10.1186/s13059-015-0781-3 Text en © Zhou and Robinson. 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Correspondence
Zhou, Xiaobei
Robinson, Mark D.
Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title_full Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title_fullStr Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title_full_unstemmed Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title_short Do count-based differential expression methods perform poorly when genes are expressed in only one condition?
title_sort do count-based differential expression methods perform poorly when genes are expressed in only one condition?
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599205/
https://www.ncbi.nlm.nih.gov/pubmed/26450178
http://dx.doi.org/10.1186/s13059-015-0781-3
work_keys_str_mv AT zhouxiaobei docountbaseddifferentialexpressionmethodsperformpoorlywhengenesareexpressedinonlyonecondition
AT robinsonmarkd docountbaseddifferentialexpressionmethodsperformpoorlywhengenesareexpressedinonlyonecondition

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