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Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

A response to ‘Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data’ by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D in Genome Biology, 2013, 14:R95 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaobei, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599205/
https://www.ncbi.nlm.nih.gov/pubmed/26450178
http://dx.doi.org/10.1186/s13059-015-0781-3