Deficiency of caspase 3 in tumor xenograft impairs therapeutic effect of measles virus Edmoston strain

The oncolytic measles virus Edmonston (MV-Edm) strain shows considerable oncolytic activity against a variety of human tumors. In this study, we report MV-Edm is able to trigger apoptosis pathways in infected tumor cells and elucidate the roles of cellular apoptosis in the whole oncolytic process. W...

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Detalles Bibliográficos
Autores principales: Wang, Biao, Yan, Xu, Guo, Qingguo, Li, Yan, Zhang, Haiyan, Xie, JiSheng, Meng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599253/
https://www.ncbi.nlm.nih.gov/pubmed/25909216

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