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Novel cross-talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses
The insulin-like growth factor-I receptor (IGF-IR), plays a key role in regulating mammalian development and growth, and is frequently deregulated in cancer contributing to tumor initiation and progression. Discoidin domain receptor 1 (DDR1), a collagen receptor tyrosine-kinase, is as well frequentl...
Autores principales: | Malaguarnera, Roberta, Nicolosi, Maria Luisa, Sacco, Antonella, Morcavallo, Alaide, Vella, Veronica, Voci, Concetta, Spatuzza, Michela, Xu, Shi-Qiong, Iozzo, Renato V., Vigneri, Riccardo, Morrione, Andrea, Belfiore, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599258/ https://www.ncbi.nlm.nih.gov/pubmed/25840417 |
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