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Phosphorylation of interleukin (IL)-24 is required for mediating its anti-cancer activity

Interleukin (IL)-24 is a tumor suppressor/cytokine gene that undergoes post-translational modifications (PTMs). Glycosylation and ubiquitination are important for IL-24 protein stabilization and degradation respectively. Little is known about IL-24 protein phosphorylation and its role in IL-24-media...

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Detalles Bibliográficos
Autores principales: Panneerselvam, Janani, Shanker, Manish, Jin, Jiankang, Branch, Cynthia D., Muralidharan, Ranganayaki, Zhao, Yan D., Chada, Sunil, Munshi, Anupama, Ramesh, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599269/
https://www.ncbi.nlm.nih.gov/pubmed/26009991